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Those with co-occurring obesity or type 2 diabetes may be eligible for GLP-1 agonist therapy for these licensed indications, and any observed effects on alcohol consumption could be monitored and reported as part of ongoing research efforts

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This finding made Trulicity an increasingly popular off-label option for weight management

It has been speculated that the continued use of bethanechol may result from its use in patients who find the option of undergoing urinary catheterisation intimidating & choose to exhaust less invasive treatment options first, or in select patients where it seems to provide a marginal benefit (Gaitonde et al, 2019)