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Mangoni, M
The trans-3-hexenoic acid group sterically shields the N-terminal region from dipeptidyl peptidase IV (DPP-IV) cleavage, which is the primary route of GHRH degradation in vivo, resulting in meaningfully improved metabolic stability compared to native GHRH and sermorelin
Drager 2013
Experimental data suggest it may help maintain the integrity of the gastrointestinal lining and support repair of the mucosal barrier under stress conditions
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