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Sermorelin and Tesamorelin are synthetic analogs of GHRH, meaning they have a structure similar to GHRH, but differing from it in respect to a certain component
Phase 3 trials include a 4mg maintenance arm specifically because some individuals achieve excellent results at lower doses
The slightly lower result at 12mg (23.2%) likely reflects the smaller sample size at this dose rather than diminishing returns, though further research will clarify this relationship
You don't just give every patient the same medication
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