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Following treatment discontinuation (after 2 years, or earlier due to non-response or adverse events), treatment effects were assumed to decline according to a catch-up rate until BMI returned to baseline
Taste receptor cells generate oscillating receptor potentials by activating G protein-coupled taste receptors
That is the entire logic behind the slow, roughly four-week-per-step escalation ladder documented in the label and the trials: it trades a few extra weeks for dramatically better gastrointestinal tolerability
Certain patterns, medical histories, and nutrition habits make some people more vulnerable
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