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Beyond Nausea: Secondary and Emerging Side Effects While gastrointestinal effects dominate, GLP-1 injections may also produce fatigue, headache, appetite suppression beyond intended effects, and muscle loss in some patientsparticularly during rapid weight loss
While on tirzepatide, patients may be advised to avoid other medications that can increase the risk of hypoglycemia when used concurrently, such as insulin or sulfonylureas
People with epilepsy who experience significant weight loss should discuss the potential need for medication adjustments with their healthcare provider
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