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In lab research models, intranasal NAD+ supply offers two key benefits over oral use: it bypasses GI breakdown (NAD+ is sensitive to acidic conditions in the stomach) and it provides direct access to the CNS via olfactory nerve transport routes, independent of blood-brain barrier permeability
Continued progress is needed to ensure these options are available and affordable for all who seek them
Small studies can miss important details
Patients can still get coverage if they have a diagnosis of Type 2 diabetes, cardiovascular disease or sleep apnea, but not if they have obesity only or for weight loss generally
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