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TB stands for TB-500 (thymosin beta 4)

Moreover, Syn-S129p triggers protein-protein interactions by inducing conformational changes within the C-terminal region, which are essential for mediating Syn function at the synapse and within the nucleus 71,73,89

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Although exploratory experimental studies currently indicate that ferroptosis is involved in the pathology of DN and can be targeted and intervened pharmacologically, the detailed mechanism still needs to be elucidated