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Genetic inactivation of hypoxia inducible factor 1-alpha (HIF-1alpha) in adult hippocampal progenitors impairs neurogenesis and pattern discrimination learning
The Bottom Line The core protocol: 100 to 300 mcg subcutaneously, 30 to 60 minutes before bed, cycled 2 to 4 weeks on and 2 weeks off
Similarly, infusion of DNA methylation inhibitors into the CA1 region of the hippocampus disturbs the hippocampal tasks, such as learning and memory consolidation, despite the increased levels of Bdnf transcripts (Miller and Sweatt, 2007
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