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K-means clustering analysis of amplicon sequence variants by animal demonstrated that NNMTi-treated DIO mice switched to LD had a distinct microbiome pattern that was highlighted by decreased Erysipelatoclostridium and increased Lactobacillus relative abundances compared to vehicle counterparts
Research in animal models indicates that elevated NNMT expression is associated with reduced levels of the glucose transporter GLUT4
For most patients, it resolves substantially after the first few weeks of a given dose
Also advise of any health or medication changes
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