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Vanillic acid restores homeostasis of intestinal epithelium in colitis through inhibiting CA9/STIM1-mediated ferroptosis
And its a crucial component of the bodys detox mechanisms
In rodent models, high-AGE diets reduced microbial diversity and the abundance of saccharolytic bacteria, while increasing potentially harmful species of Desulfovibrio and Bacteroides , and elevating toxic microbial metabolites like cresol and putrescine (133, 134)
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