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Foods such as chips, pastries, full-fat takeaways, and heavily buttered dishes slow gastric emptying even further, compounding the drug's existing effect and increasing the risk of nausea, vomiting, and upper abdominal discomfort
The medication is administered as a once-weekly subcutaneous injection, with dosing gradually increased over several weeks to minimize gastrointestinal side effects
In some cases, it might be psychological
However, the repair tissue is often accompanied with undesirable chondrocyte hypertrophy and terminal differentiation, which cause matrix degradation and then impair the function of the repair tissue
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