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Dihexa (PNB-0408 / N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide) is a blood-brain barrier permeable oligopeptide analog derived from Angiotensin IV
For research protocols using the 10mg or 12mg maintenance dose, the injection volume should be accounted for in the reconstitution plan
This is the most important caveat for beginners, and the one most vendor pages omit
GSH is synthesized de novo in the brain by astrocytes and research has demonstrated increased GSH synthesis during oxidative stress-related toxicity in vitro , proposing in vivo synthesis of this antioxidant might be sufficient to not detect significant changes (14)
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