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The results of HE staining showed that compared with the control group, the model group had swollen hepatocytes and vacuolar changes (mainly steatosis)
For Rybelsus (oral semaglutide), diarrhea was reported in 7.5-8.5% of patients depending on the dose, compared to 4.1% with placebo
Conclusions GLP-1 analogues are an effective treatment for weight loss, and the addition of bupropion/naltrexone is associated with greater weight loss including in patients who are initially non-responsive to GLP-1 analogues
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