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A larger phase IIb trial of intranasal glutathione (300 mg/dose, three times daily for 3 months, n=45) also showed no significant improvement over placebo (Mischley et al., J Parkinsons Dis, 2017) [52]
Researchers have therefore investigated whether CoQ10 supplementation can help support oocyte quality and reproductive outcomes.53 54 Systematic reviews suggest CoQ10 may improve certain outcomes in women undergoing assisted reproductive technology, including clinical pregnancy rates in some analyses.55 56 Ritual's 100mg dose is lower than many fertility studies, which often use 200600mg daily, but it still adds a relevant mitochondrial-support ingredient to the formula
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