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The molecule has the same affinity for human PCSK9 as Ab#2.1 and cross-reacted with cynomolgus and rat PCSK9 (Supplementary Table 7)

Beninger RJ, Phillips AG (1980)

Presently, the plethora of identified NRF2 activators is of electrophilic nature and targets the reactive cysteine residues of KEAP1