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886 The intestinal microbiota metabolite capsiate is negatively correlated with cartilage degeneration score in OA mice, and capsiate reduces ferroptosis dependent osteoarthritis both in vivo and in vitro, through activation of SLC2A1 and inhibition of HIF-1
waist circumference was measured at baseline, week 20, and annually
Most reported side effects are mild, but serious symptoms need medical attention
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