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more common in darker skin) Symptoms * New or changing mole * Itching or bleeding lesion * Dark, irregular skin patch * Non-healing skin sore Diagnosis * Skin examination (dermoscopy) * Excisional biopsy (preferred for confirmation) * Imaging if spread suspected (CT, PET scan) Staging (basic idea) * Stage 0: in situ (confined to epidermis) * Stage III: localized tumor * Stage III: lymph node involvement * Stage IV: distant metastasis Treatment Depends on stage: Early stage * Surgical removal (wide local excision) * Sentinel lymph node biopsy Advanced stage * Immunotherapy (e.g., checkpoint inhibitors) * Targeted therapy (for BRAF mutation) * Radiotherapy (palliative use) * Chemotherapy (less commonly used now) Prognosis * Excellent if detected early * Poor once metastasis occurs * Early detection is the most important factor Prevention * Avoid excessive sun exposure * Use sunscreen (SPF 30+) * Wear protective clothing * Avoid tanning beds * Regular skin self-examination Melanoma Risk Factors and Warning Signs Melanoma is a malignant tumor of melanocytes (cells that produce melanin pigment in the skin)