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If youre on a lower dose, discuss with your InstaClinic provider about safely increasing it

Practical Considerations and Expert Perspectives While the initial findings are exciting, its crucial to listen to what experts in the field are saying

In a 10-week clinical trial, a daily dose of 20 mg oral semaglutide achieved a steady-state plasma concentration of 30 nM, and when daily dose of oral semaglutide was increased to 40 mg, the semaglutide plasma concentration reached about 60 nM (102), which was over a thousand times higher than the EC50 of semaglutide for GLP-1R activation (95)