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One of the most striking modern findings came from a Broad Institute analysis using the Connectivity Map database

Chronic ketamine exposure in rodent models (50 mg/kg daily for 8 weeks) leads to significant activation of microglial cells and elevated expression of proinflammatory cytokines, such as IL-6 and IL-1, which correlate with hippocampal neuronal damage (Yin et al., 2022)

Ozempic and Wegovy share the same active ingredient, semaglutide, but are approved for different conditions and dosages