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Las opciones teraputicas incluyen: Aminosalicilatos (mesalamina, sulfasalazina) para enfermedad leve a moderada Corticosteroides para brotes agudos, uso limitado por efectos adversos Inmunomoduladores (azatioprina, 6-mercaptopurina) para mantenimiento Terapias biolgicas (anti-TNF, anti-integrinas, anti-IL-12/23) para enfermedad moderada a severa Inhibidores de JAK como opcin ms reciente Moduladores del receptor S1P (ozanimod) para enfermedad moderada a severa La seleccin del tratamiento depende de la extensin y severidad de la enfermedad, respuesta previa a terapias, y perfil de riesgo individual
[13] Transcription factors [edit] Peroxisome proliferator-activated receptor alpha (PPAR ) is a nuclear receptor that functions as a transcription factor
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Connective tissues include: Tendons Ligaments Fascia Cartilage support structures Skin matrix Joint-supporting tissues These tissues heal slowly because they often have limited blood supply
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