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Retatrutide is studied as acting on the GLP-1, GIP and glucagon receptors (a triple agonist)
Starting at a low dose can assist with these issues
GLP-1 receptor agonists promote weight loss through reduced appetite, increased feelings of fullness, and delayed gastric emptying
Efficacy and safety of once-weekly semaglutide versus exenatide ER in subjects with type 2 diabetes (SUSTAIN 3)
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