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Conversely, venglustat, a glucosylceramide synthase inhibitor, failed to show any clinical benefit over placebo in GBA1-related PD in part 2 of a recent phase 2 trial [126], after having demonstrated favourable safety, tolerability, and target engagement in the cerebrospinal fluid (CSF) in part 1 of the same trial [127]
Hng dn s dng Gluthion 1200 iu tr cho bnh nhn: S dng 3000 600mg/ln/ngy (tng ng l) iu tr cho bnh nhn nng: S dng 600 1200mg/ln/ngy (tng ng 1 l) Lu : C th tim bp hoc tnh mch chm
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