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There may be also issues with instability and degradation (vitamins E and C are quite prone to degradation in solutions) or low interaction of the semi-synthetic derivatives with the delivery systems (such as sodium-dependent vitamin C transporters)
R., Guan, X
(PubMed) Parisi V, Coppola G, Ziccardi L, Gallinaro G, Falsini B
Several other genes associated with sugar and lipid transport or metabolism were also significantly upregulated in symbiotic branches, as would be expected given the nutritional exchanges that occur between coral hosts and their algal symbionts (Fig
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