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The formula uses stable, non-irritating Vitamin C derivatives rather than L-Ascorbic Acid, which is the main culprit behind the stinging and redness people associate with potent Vitamin C products
DOI Campbell JD, McDonough JE, Zeskind JE, et al
Within the ligand-bound structures of S -THIQspecific variants (S2.3 and S2.4), a negatively charged glutamate introduced by the C135E mutation strongly interacts with the protonated amine of S -THIQ by salt-bridge interactions (2.7 and 2.5 in distance, respectively
Br J Haematol 166:496513
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