1,4 Hyperglycemia, dyslipidemia, and insulin resistance activate various metabolic pathways, resulting in oxidative stress, mitochondrial dysfunction, inflammation, and microvascular damage, culminating in neuronal injury, Schwann cell damage, and myelin sheath degeneration
Long-term glutathione supplementation has been associated with reduced zinc concentrations, which can result in many health problems
GLP-1 agonist weight loss medications like Wegovy and Saxenda have a high probability of causing thyroid cancer based on available evidence These medications were originally designed for diabetes and then repurposed for weight loss, which means the long-term thyroid safety data is still limited The potential benefits of GLP-1 agonists for weight loss must be carefully weighed against the significant risk of developing thyroid cancer If you're considering these medications, have a detailed conversation with your doctor about your personal thyroid cancer risk versus the weight loss benefits Do the most popular weight loss medications of our time like Wegovy and Saxenda cause thyroid cancer
This study received approval from the SingHealth Centralized Institutional Review Board (CIRB Ref: 202008-00040), and all participants provided written informed consent
