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However, skipping multiple weeks or months may reset your steady-state levels and cause appetite return, potentially requiring dose re-titration

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It has mild peeling effect which is again, something that I like

Common side effects: Headache Upper respiratory infection symptoms (sore throat, runny/stuffy nose) Constipation Vomiting Mouth ulcers Rare but serious side effects (seek medical attention): Heart failure (shortness of breath, swelling, sudden weight gain) Pancreatitis (persistent nausea/vomiting, severe abdominal/back pain) Allergic reactions (hives, facial swelling, difficulty breathing) Hypoglycemia when combined with insulin or sulfonylureas (hunger, sweating, confusion) Kidney problems (decreased function, failure requiring dialysis) Severe skin reactions (blisters, skin erosion) Severe joint pain What should you tell your healthcare provider before taking Januvia