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Overall, GLP-1 show promise as a new treatment approach for smoking cessation and could be a valuable addition to existing strategies
Similarly, the highly anticipated EVOKE and EVOKE+ phase 3 trials of oral semaglutide in early Alzheimers disease reported in November 2025 that semaglutide failed to meet its primary endpoints : while it reduced several AD-related biomarkers by up to 10%, these changes did not translate into cognitive or functional benefit ( [72] )
10.1136/bmj.317.7173.1624 158 WheatleyL
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