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More clinically significant concerns include: IGF-1 excess: Supraphysiologic IGF-1 has been associated with increased risk of colorectal and other cancers in epidemiological studies, though causation is not established [9]

Manufacturers compensate by using peptide fragments or lipid-conjugated peptides that absorb more readily, but these are workarounds, not solutions

The primary antibodies used were as follows: -actin (Proteintech, 20536-1-AP, 1:1,000 dilution), p-YAP1 (Abmart, T55743, 1:10,000 dilution), YAP1 (Abmart, PAQ6610, 1:1,000 dilution), p-LATS1/2 (Abmart, TA8163, 1:1,000 dilution), LATS1 (Abmart, PA3032, 1:1,000 dilution), p-MST1/2 (Abmart, P42569-3, 1:1,000 dilution), and MST1/2 (Abmart, TD8569, 1:1,000 dilution)

The role of other molecules for this control is also important and may increase the complexity in the understanding of these mechanisms