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The physiological effects of GLP-1 medications like Ozempic and Wegovy profoundly impact appetite and satiety, often leading to reduced food intake
Lam KN et al (2021) Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome
(2023) revealing reductions in abdominal obesity and inflammation, although muscle mass was not assessed [112]
Subsequent trials, including REWIND (dulaglutide) and LEADER (liraglutide), did not demonstrate increased retinopathy risk
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