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The empty-stomach timing matters because ghrelin-pathway secretagogues like Ipamorelin are suppressed when insulin is elevated from a recent meal
Eating well also means making sure your body gets enough fuel and protein to maintain muscle mass while losing weight
Together, these dynamics underpin a robust growth trajectory
The Endocrine Society's 2023 clinical practice guideline on male hypogonadism explicitly states that clinicians should "recommend weight loss before initiating testosterone therapy in men with obesity-related functional hypogonadism" [4]
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