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Prior authorization requirements are common, requiring documentation of BMI over 30 kg/m or over 27 kg/m with comorbidities, failed attempts at diet and exercise, and sometimes trial of other weight loss medications

The low absolute event frequency observed in both cohorts suggests that optic nerve ischemic events are uncommon in this population, the authors wrote in their paper

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NP4 reached a maximal oxygen storage of 53 mg/L, which was approximately 2.5 more than for NP2 (Supplementary Fig