Central appetite suppression delayed gastric emptying, and potential remodeling of adipose tissue contribute to an overall improvement in metabolic health, which is expected to benefit patients with MASLD
The goal of the study was to ascertain whether GI adverse events (GI AEs), such as nausea/vomiting, diarrhea, constipation, and dyspepsia (indigestion), during the dose escalation phase (baseline to week 12) and from baseline to the end of treatment, are responsible for the greater weight loss seen with semaglutide compared to other GLP-1RAs
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Liberado pelo intestino aps as refeies, o GLP-1 (glucagon-like peptide-1) estimula a produo de insulina , substncia que diminui a taxa de glicose no sangue