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Description

Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg for 4 weeks (a non-therapeutic initiation dose to improve tolerability), then increased every 4 weeks to reach a therapeutic dose of 5-15 mg weekly based on response and tolerability

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Using liraglutide (Lira) as a model GLP-1 receptor agonist, these NPs effectively alleviated diabetic symptoms in db / db mice [176]

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