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Preclinical evidence supports the role of GLP-1RAs in alleviating neuropathic pain through the modulation of microglial activity, inflammatory cytokine production and -endorphin release [63, 65, 68, 70,71,72,73,74]

This delayed stomach emptying contributes to feelings of fullness and reduced appetite, which supports therapeutic goals

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GLP-1 medications work by mimicking natural hormones in the gut, which help to lower blood sugar, slow digestion, and promote feelings of fullness to aid weight loss