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Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (surmount-2): A double-blind, randomised, multicentre, placebo-controlled, phase 3 trial
Eventually, beta cell exhaustion progresses beyond the point of compensation
Paracetamol (5001000 mg every 46 hours, maximum 4 g daily) represents a safe first-line option for most patients
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