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15 Whether the pro-oxidant glutathione redox imbalance previously observed in plasma and immune cells from children with autism is also present in the autism brain has not been investigated

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More recently, a family of potent and highly selective mechanism-based suicide substrate inhibitors were developed and shown to promote the irreversible inhibition of gut microbiotadependent generation of TMA, suppression of host TMAO levels, and, in parallel, inhibition of platelet hyperresponsiveness and thrombosis potential in animal models (22)