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Something else was happening at the level of the blood vessels themselves

Although direct mechanisms by which microglia interact with mature OLs to regulate their responses are not clear, a study in zebrafish showed that microglia engulf myelin sheaths to regulate sheath number in developmental myelination 174

Loading Phase Amount: 250500mcg daily Duration: Until desired pigmentation-related observations are achieved (commonly 714 days) Maintenance Phase Amount: 250500mcg Frequency: 23 times weekly Administration Subcutaneous administration (abdomen or thigh) Optional Timing Evening administration is commonly utilized in research settings to potentially reduce flushing- or nausea-related observations