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In order to evaluate the mechanisms of action of tirzipatide, in a recent study [62] subjects with T2DM performed a deep metabolic evaluation with measures of beta cell function and insulin sensitivity by hyperglycemic clamp, mixed meal test and euglycemic clamp before and 28 weeks after treatment with tirzepatide 15 mg or semaglutide 1 mg
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Alternatives to semaglutide If you are interested in a GLP-1 besides semaglutide, the main alternatives are liraglutide (Victoza is for type 2 diabetes while Saxenda is approved for weight loss) and tirzepatide (Mounjaro is approved for type 2 diabetes and Zepbound is for weight loss)
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