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A peer-reviewed study in the Journal of Endocrinology confirming that AOD9604 produces lipolysis and increases fat oxidation in obese mice via the beta-adrenergic pathway, with effects comparable to full-length HGH but without the insulin-disrupting side effects provided early mechanistic validation that informed the human trials

A Vitamin B12 deficiency can lead to weight changes, although the effects can vary from person to person

Advocates of this approach claim that regular injections can boost energy levels and help with weight loss and mood