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In addition, three of the five included studies showed a reduction in cardiovascular events, especially in patients with DM2 and high CV risk
In phase 2 studies of ELAINE-1 and ELAINE-2, lasofoxifene demonstrated significant antitumor activity in patients with ESR1 -mutated, endocrine-resistant metastatic breast cancer
doi:10.1263/jbb.105.409 Xiong Z, Guo M, Guo Y, Chu J, Zhuang Y, Wang NS, Zhang S (2010) RQ feedback control for simultaneous improvement of GSH yield and GSH content in Saccharomyces cerevisiae T65
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