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The placebo group had either an increase or no change in oxidative stress, as shown by a significant increase in MDA in RBCs ( Figure 4E ) or no change in MDA in plasma ( Figure 4C ) or PBMCs ( Figure 4D )
Sultana F, Manirujjaman M, Imran-Ul-Haque M, Arafat S (2013) Sharmin, An overview of nanogel drug delivery system
These changes lead to central sensitization, where non-painful stimuli are perceived as painful (allodynia), and pain responses are amplified (hyperalgesia)
Exhibits anti-inflammatory and protective effects in preclinical settings
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