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Contrariwise, other relevant aspects, such as the safety profile and tolerability of GLP-1RA or the beneficial effects on fertility in PCOS, have been more extensively treated, especially considering that possible direct or indirect reproductive effects of GLP-1 RA might require a concomitant effective contraception and a washout period before pregnancy [22, 24,25,26,27,28,29,30,31]

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Association of glucagon-like peptide-1 receptor agonists with suicidal ideation and self-injury in individuals with diabetes and obesity: a propensity-weighted, population-based cohort study

community sources describe keeping fast-acting carbs available Organ growth gut distension and cardiomegaly possible with prolonged, high-dose use Jaw and hand growth subtle acromegaly-like changes with chronic use Cancer risk chronically elevated IGF-1 is associated with increased cancer risk in epidemiological studies Joint pain connective tissue changes, water retention Fatigue/lethargy common, especially initially Injecting before sleep community sources warn against this, as hypoglycemia during sleep is dangerous mg to Units Conversion On a standard 100-unit insulin syringe, each "unit" equals 0.01 mL (so 100 units = 1 mL)