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However, the name can be misleading
J Anal Pharm Res
[12] [13] Regulation [edit] The regulation of mammalian ACC is complex, in order to control two distinct pools of malonyl-CoA that direct either the inhibition of beta oxidation or the activation of lipid biosynthesis
Under low oxygen conditions, HIF-1 acts as a key modulator of mitochondrial metabolism, actively repressing oxidative phosphorylation (OXPHOS) to reduce cellular oxygen consumption and mitochondrial-generated reactive oxygen species (ROS), which can be toxic at high levels (78)
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