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At the molecular level, excessive androgen receptor activation has been shown to stimulate phosphoinositide-3-kinase (PI3K)/Akt and mitogen-activated protein kinase (MAPK) signalling pathways, promoting cardiomyocyte hypertrophy while simultaneously enhancing mitochondrial oxidative injury (73)

What your healthcare provider needs to know When discussing urinary changes with your provider, specific details are more useful than vague complaints

Phase 2 trials have also highlighted other possible side effects, like injection site reactions