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Such is the case for cuticle pigmentation, which was significantly darkened in 1 mM L-DOPA-fed mosquitoes (Fig
This difference is likely to be related to the more tightly packed ECD interface of RAMP2 and CTR, driven by the interactions with P37 Cagri , and the preferential CTR engagement by Cagri via a bypass conformation, as discussed below in the context of CTR complexes
11B and D) provide an approximation of expected real-world predictive performance, whereas the higher PPVs observed in Fig
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