The body naturally produces insulin, a hormone responsible for regulating blood sugar
Pirro V, Roth KD, Lin Y, Willency JA, Milligan PL, Wilson JM, Ruotolo G, Haupt A, Newgard CB, Duffin KL
This figure integrates medications with the population phenotype (type 2 diabetes with or without CKD, and non-diabetic CKD with obesity), CKD stage, and renal outcome domains (albuminuria, eGFR slope, and hard kidney outcomes), using a GRADE-informed approach
Many underlying issues remain untouched, including: Hormonal imbalances Insulin resistance Chronic inflammation Poor gut health Stress-related cortisol elevation Nutrient deficiencies When the medication is stopped, the body often rebounds because the root causes were never resolved