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Berberine Berberine is a plant-derived compound often used as a GLP-1 supplement because research suggests it may stimulate GLP-1 secretion and improve glucose metabolism, though much of the evidence so far comes from laboratory, animal, and smaller human studies rather than large clinical trials
A major finding in the present work was that GLP-1/exendin-4 significantly suppressed GABA currents in rat GCs by activating GLP-1R
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