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Description

Using synthetic DPP4 inhibitors requires a high degree of selectivity in order to achieve an optimal safety profile

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Administration of spironolactone, a selective MR antagonist, counteracted stress-induced mGlu2 suppression and the related development of depressive-like behavior, implicating rapid action of glucocorticoids via a receptor that is known to modulate glutamate release [20]

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[10] Strehle EM

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