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Alternative to surgery in some cases: For individuals hoping to avoid surgery (e.g., for tendon repair, ligament injury), the stack is sometimes promoted as a less invasive option, though this claim is based mostly on animal data and anecdotes
Creatine supplementation combined with regular resistance exercise has a well-established evidence base for supporting muscle mass and strength during significant weight loss, making its use physiologically plausible alongside retatrutide, though the specific combination has not been studied in clinical trials
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