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The amino acid sequence is in the public domain and there is no composition-of-matter patent worth pursuing, so no commercial sponsor will fund the hundreds of millions a Phase IIIII development programme costs for a compound it cannot exclusively monetise

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Shaking the vial to speed up dissolution is the most common, and its also the one most likely to degrade the peptide rather than simply mix it

Drawing the Medication Swab the Vial : Cleaning : Use an alcohol swab to clean the rubber stopper on the top of the B12 vial